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There is a gradual decline in testosterone with age, but few men (<6%) reach true hypogonadism and less than 12% of men with ED are hypogonadal.
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Men with a history of CVD, a major comorbidity of ED, presented a dilemma for physicians and patients. Is obesity an underlying factor in erectile dysfunction. The side effects were those typically seen in all the sildenafil trials: transient headaches (28.
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